ADDISON, Thomas On the constitutional and local effects of disease. London: Samuel Highly, 1855
FIRST EDITION., 4to., viii, 43 , [1] pp.
With 11 coloured lithographed plates. Original cloth, spine expertly restored; top corner a bit worn, minor marginal stains. Wellcome Library's unobtrusive withdrawal stamp on verso of title; a highly desirable copy in original state, preserved in a handsome quarter-morocco slipcase. , First edition of one of the great rarities in the history of medicine, and the foundation of modern endocrinology. Addison describes two major diseases for the first time, presenting his remarkable discoveries in a series of eleven detailed case histories illustrated with fine hand-coloured plates. G&M, 3864.
$US15000
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